Matthew Perry's Ketamine Use 'Likely Recreational', report says

Perry's Autopsy Reveals Concerning Substance Use Details

by Zain ul Abedin
Matthew Perry's Ketamine Use 'Likely Recreational', report says
© Ronald Martinez/Getty Images

The untimely passing of Matthew Perry, the beloved star known for his role in the iconic sitcom "Friends," has left fans and the entertainment industry in shock. Perry, who passed away on October 28, 2023, at the age of 54, is now at the center of a concerning discussion following the disclosure of his autopsy report.

The report, which surfaced in a recent Page Six article, indicates the presence of ketamine in his system, sparking debates about its intended use. The autopsy report sheds light on Perry's struggle with mental health, revealing that he had been undergoing ketamine infusion therapy to combat depression and anxiety.

Ketamine, often used in this therapeutic context, has been recognized for its potential in treating such conditions. However, the report's details suggest a more complex scenario.

Risky Drug Combination

Dr. Bankole Johnson, a renowned neuroscientist and physician, expressed alarm at the combination of drugs found in Perry's system.

The report not only mentioned ketamine but also highlighted the presence of buprenorphine, an opioid-like substance. Dr. Johnson pointed out that prescribing ketamine to someone also taking buprenorphine would be highly unusual and potentially dangerous.

This combination, he remarked, could be a "true recipe for disaster." Such concerns raise the possibility that Perry's use of ketamine may have been recreational rather than medicinal. The circumstances of acquiring ketamine are under scrutiny, as it is not readily available over the counter or through a prescription for self-medication purposes.

Multiple Health Struggles

Further complicating the picture, the report disclosed that Perry was also taking Tammoxifen, a medication commonly associated with weight loss efforts, alongside nicotine lollipops for smoking cessation and antidiabetic medication.

These findings paint a picture of a man grappling with multiple health challenges. In a telling insight into Perry's final days, a close female friend revealed to Page Six that he had been unusually "angry and mean." This behavioral change was attributed to testosterone shots Perry had been taking.

Matthew Perry's death has opened a window into individuals' often-hidden struggles in the public eye. His story is a poignant reminder of the complex interplay between mental health, substance use, and the pressures of fame.

As fans mourn his loss, the conversation around his final days underscores the need for a deeper understanding and more compassionate approach to mental health and substance use disorders.

Matthew Perry