Chris Hemsworth learned during the filming of an episode of the series "Limitless" that due to the combination of genes, he has almost 10 times more chance of getting Alzheimer's disease. The "Thor" actor learned in an episode of the Disney+ and National Geographic limited series "Limitless" — which shows him exploring ways to extend life and fight aging — that he has two copies of the APOE4 gene, one from each of his parents, meaning that has an increased predisposition to the development of Alzheimer's disease.
"Yeah, they took all my bloodwork and did a bunch of tests and the plan was to on-camera tell me all the results and then talk about how you can improve this and that. And Peter Attia, who is the longevity doctor in that episode, and overseeing a lot of the show, called [show creator] Darren [Aronofsky] and said, “I don't want to tell him this on camera.
We need to have an off-side conversation and see if he even wants this to be in the show”. It was pretty shocking because he called me up and he told me.
APOE4 is not a predeterministic gene, but a strong indication
He also said the show then "became even more relevant and important to him, even more moving than he ever thought it would be," adding that APOE4 is not a predeterministic gene, but a strong indication: "Yeah, it's like one in a thousand people…or one in 10,000.
I can't remember. But eight to 10 times more likely. Since you told me that, I feel like my memory's getting worse. It's a placebo effect—or it's taking place! [Laughs]," he says in a clip from the series. The new information, which Hemsworth said made him "eight to 10 times more likely" to eventually develop Alzheimer's disease, naturally led him to reflect on death and his own mortality.
"Limitless," which shows the Marvel star engaging in various stunts and practices to prolong and improve his life, actually deals with facing death in its final episode.